Development of polycaprolactone/hydroxyapatite composite resin for 405 nm digital light projection 3D printing
| Autor: | Yuan Min Lin, Chih Hsin Lin, Pin Ju Huang, Shyh Yuan Lee, Hsuan Chen |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0209 industrial biotechnology
Materials science Flexural modulus Mechanical Engineering Composite number 02 engineering and technology 021001 nanoscience & nanotechnology Acryloyl chloride Industrial and Manufacturing Engineering chemistry.chemical_compound 020901 industrial engineering & automation Monomer Flexural strength chemistry Polymerization Polycaprolactone Composite material 0210 nano-technology Photoinitiator |
| Zdroj: | Rapid Prototyping Journal. 26:951-958 |
| ISSN: | 1355-2546 |
| DOI: | 10.1108/rpj-06-2019-0166 |
| Popis: | Purpose The purpose of this study is to develop resin composite materials composed of polycaprolactone (PCL) acrylates and hydroxyapatite (HA) nanoparticles for ultraviolet digital light projection (DLP) three-dimensional (3D) printing technique. Design/methodology/approach Two PCL-based triacrylates, namely, glycerol-3 caprolactone-triacrylate (Gly-3CL-TA) and glycerol-6 caprolactone-triacrylate (Gly-6CL-TA) were synthesized from ring-opening polymerization of ε-caprolacton monomer in the presence of glycerol and then acrylation was performed using acryloyl chloride. 3D printing resins made of Gly-3CL-TA or Gly-6CL-TA, 5% HA and 3% of photoinitiator 2,4,6-Trimethylbenzoyl-diphenyl-phosphineoxide were then formulated. The surface topography, surface element composition, flexural strength, flexural modulus, cytotoxicity and degradation of the PCL-based scaffolds were then characterized. Findings Resin composite composed of Gly-3CL-TA or Gly-6CL-TA and 5% (w/w) of HA can be printed by 405 nm DLP 3D printers. The former has lower viscosity and thus can form a more uniform layer-by-layer structure, while the latter exhibited a higher flexural strength and modulus after being printed. Both composite materials are non-cytotoxic and degradable. Originality/value This study provides a direction of the formulation of environment-friendly resin composite for DLP 3D printing. Both resin composites have huge potential in tissue engineering applications. |
| Databáze: | OpenAIRE |
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