ChemInform Abstract: Vicinal Bisheterocyclizations of Alkynes via Nucleophilic Interception of a Catalytic Platinum Carbene

Autor:	Paul Allegretti, Eric M. Ferreira
Rok vydání:	2014
Předmět:	chemistry.chemical_compound chemistry Nucleophile chemistry.chemical_element Reactivity (chemistry) General Medicine Platinum Combinatorial chemistry Carbene Vicinal Catalysis
Zdroj:	ChemInform. 45
ISSN:	0931-7597
DOI:	10.1002/chin.201423118
Popis:	A novel platinum-catalyzed double heterocyclization of propargylic ethers is described. The transformation exploits the intermediacy of a key α,β-unsaturated carbene. The reactivity of this carbene is such that systems can be developed which avoid a complicating 1,2-hydrogen migration, allowing remarkable versatility in the selective syntheses of oxygen- and nitrogen-containing vicinal bis-heterocyclic compounds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b408ab1369610680dfabe8cd41c4bc88 https://doi.org/10.1002/chin.201423118 Zobrazit plný text záznamu Plný text