ChemInform Abstract: 4-Acetylamino-3-(imidazol-1-yl)-benzoic Acids as Novel Inhibitors of Influenza Sialidase
Autor: | Helen Feilden, Paul W. Smith, Peter D. Howes, Derek N. Evans, Neil Taylor, Anne Cleasby, Alan J. Wonacott, Steven L. Sollis |
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Rok vydání: | 2010 |
Předmět: | |
Zdroj: | ChemInform. 30 |
ISSN: | 1522-2667 0931-7597 |
Popis: | Two methods for the synthesis of 4-acetylamino benzoic acids substituted at the 3-position with imidazoles are described. Many of the compounds are inhibitors of influenza virus sialidases with levels of activity similar to the recently described 4-acetylamino-3-guanidino-benzoic acid (BANA 113). |
Databáze: | OpenAIRE |
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