The porcine hormone-sensitive lipase gene: sequence, structure, polymorphisms and linkage mapping

Autor: A. G. Ege, B. Høyheim, M. Langset, I. Harbitz, W. Davies
Rok vydání: 1999
Předmět:
Zdroj: Animal Genetics. 30:10-16
ISSN: 0268-9146
DOI: 10.1046/j.1365-2052.1999.00412.x
Popis: The porcine hormone-sensitive lipase gene and its cDNA have been isolated and sequenced. Several putative regulatory sequences have been detected in the promotor region. The deduced amino acid sequence is 85% identical to the corresponding human, mouse and rat sequence. A search for polymorphisms revealed one intronic and one exonic polymorphism, the latter resulting in a conservative amino acid substitution. Linkage mapping located the LIPE gene close to the calcium release channel (CRC) locus on chromosome 6.
Databáze: OpenAIRE