SY02-4IMPACT OF DOPAMINE DEPLETION OR ENHANCEMENT ON ETHANOL CONSUMPTION IN RATS: FREE VERSUS WORK-MEDIATED ACCESS
Autor: | J. D. Salamone, Noemí SanMiguel, L. Monferrer, J. M. Perez-García, J. Camañes, C. Carratalà, Laura López-Cruz, Mercè Correa |
---|---|
Rok vydání: | 2015 |
Předmět: | |
Zdroj: | Alcohol and Alcoholism. 50:i4.1-i4 |
ISSN: | 1464-3502 0735-0414 |
DOI: | 10.1093/alcalc/agv076.07 |
Popis: | Nucleus accumbens dopamine (DA) plays a critical role in behavioral activation and effort-based decision-making. DA depletions reduce the level of effort that an animal is willing to make to obtain a natural reinforcer, but it does not change preference between freely available reinforcers. On the other hand, drugs whose mechanism … |
Databáze: | OpenAIRE |
Externí odkaz: |