ChemInform Abstract: Deprotection of Carboxylic Esters of β-Lactam Homologues. Cleavage of p-Methoxybenzyl, Diphenylmethyl, and tert-Butyl Esters Effected by a Phenolic Matrix

Autor:	Sigeru Torii, Michio Sasaoka, Yutaka Kameyama, Takashi Shiroi, Masatoshi Taniguchi, A. Shimabayashi, Ryo Kikuchi, Shigemitsu Nagao, Hideo Tanaka, Ichiro Kawahara
Rok vydání:	2010
Předmět:	Tert butyl Matrix (chemical analysis) chemistry.chemical_compound chemistry Lactam Phenol General Medicine Cleavage (embryo) Medicinal chemistry
Zdroj:	ChemInform. 22
ISSN:	0931-7597
DOI:	10.1002/chin.199141095
Popis:	p-Methoxybenzyl, diphenylmethyl, and tert-butyl esters were deprotected by gentle heating in phenol. This method of ester cleavage played an important role in β-lactam synthesis. The mechanism of the reaction is believed to involve a proton relay through a hydrogen-bonded phenolic matrix
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b3bcd7d2e939a4160aaf206d72592995 https://doi.org/10.1002/chin.199141095 Zobrazit plný text záznamu Plný text