Disseminated Rhinocladiella mackenziei infection in a kidney transplant recipient: A case report and literature review
| Autor: | khalid A Atea, Torki Al-Otaibi, Abdullah M. S. Al-Hatmi, Osama Gheith, Khaled Alobaid, Sohair M Zein Eldein, Mohamed Zahab, Ayman Maher Nagib, Medhat A Halim, Amal Abd El-Azem Sadon, Tarek Mahmoud, Jacques F. Meis, Prasad Nair, Hasaneen H Aboatya, M. Balaha |
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| Rok vydání: | 2021 |
| Předmět: |
Voriconazole
Pediatrics medicine.medical_specialty biology business.industry medicine.disease biology.organism_classification Kidney transplant recipient Phaeohyphomycosis Infectious Diseases Rhinocladiella mackenziei Renal transplant medicine Renal allograft Transplant patient Solid organ transplantation business medicine.drug |
| Zdroj: | Journal of Medical Mycology. 31:101196 |
| ISSN: | 1156-5233 |
| DOI: | 10.1016/j.mycmed.2021.101196 |
| Popis: | Rhinocladiella mackenziei is a rare fungal pathogen which belongs to a large group of pigmented fungi causing phaeohyphomycosis. R. mackenziei primarily infects the brain and leads to high fatality rates among both immunocompetent and immunocompromised individuals. Among solid organ transplant recipients, the infection may disseminate to extra-neuronal sites, necessitating comprehensive radiologic imaging. Here we describe a new case of R. mackenziei infection in a renal transplant patient involving the brain and renal allograft. She received liposomal amphotericin B and voriconazole but no surgical intervention. Ultimately, the patient died after two months of hospital stay. A review of all reported cases of transplant patients infected with R. mackenziei is also presented. |
| Databáze: | OpenAIRE |
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