Enantio- and Diastereoselective Two-Pot Synthesis of Isoquinuclidines from Glutaraldehyde and N-Aryl Imines with DFT Calculations

Autor:	Rajni Kant, Amol Prakash Pawar, Nisar A. Mir, Sachin Choudhary, Indresh Kumar, Devinder Kumar Sharma, Panduga Ramaraju, Eldhose Iype
Rok vydání:	2019
Předmět:	chemistry.chemical_compound chemistry Aryl Organic Chemistry Glutaraldehyde Combinatorial chemistry
Zdroj:	The Journal of Organic Chemistry. 84:12408-12419
ISSN:	1520-6904 0022-3263
Popis:	A pot-economic method for the enantio- and diastereoselective synthesis of a [2.2.2] azabicyclic isoquinuclidine system is developed. This protocol involves the proline-catalyzed direct Mannich rea...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b398fbb3445ef882f49db5d73d533b1d https://doi.org/10.1021/acs.joc.9b01865 Zobrazit plný text záznamu