Evaluation of the antifungal activity of four solutions used as a final rinsein vitro
Autor: | Luciano Giardino, Flavio Palazzi, Zahed Mohammadi |
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Rok vydání: | 2010 |
Předmět: |
Antifungal
food.ingredient Materials science biology business.industry medicine.drug_class Chlorhexidine Dentistry biology.organism_classification In vitro Tetraclean stomatognathic diseases chemistry.chemical_compound food medicine.anatomical_structure stomatognathic system chemistry Human tooth Sodium hypochlorite medicine Agar business Candida albicans General Dentistry medicine.drug |
Zdroj: | Australian Endodontic Journal. 39:31-34 |
ISSN: | 1329-1947 |
Popis: | The aim of the study was to compare the antifungal activity of 1.3% sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX), MTAD and Tetraclean as a final rinse against Candida albicans in a human tooth model in vitro. Ninety extracted human maxillary central and lateral incisor teeth were randomly divided into four groups each with 20 teeth, a positive and a negative control each with five teeth. After preparing the root canals, teeth were inoculated with Candida albicans (ATCC 10261) and incubated for 72 h. Teeth were divided into four experimental groups according to the irrigation solution as follows: NaOCl, CHX, MTAD and Tetraclean. After culturing aliquots from the experimental teeth on Sabouraud 4% dextrose agar, colony-forming units were counted. The results showed that 1.3% NaOCl and 2% CHX were equally effective and significantly superior to MTAD and Tetraclean (P < 0.05). Furthermore, antifungal efficacy of Tetraclean was significantly superior to MTAD (P < 0.05). |
Databáze: | OpenAIRE |
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