Airway Secretory IgA Concentrations in Patients with Lung Cancer

Autor: Fredrick N. Hanson, Diana S. Dark, Lewis J. Wesselius, David L. Wheaton
Rok vydání: 1989
Předmět:
Zdroj: Chest. 95:1265-1268
ISSN: 0012-3692
Popis: To determine whether concentrations of the primary airway immunoglobulins (SIgA, IgG) are altered in the uninvolved lung of patients with lung cancer, we determined concentrations of SIgA and IgG in bronchial washings recovered from a proximal airway of the uninvolved lung in 24 patients with lung cancer and in ten patients with benign lung disease. When standardized for the amount of total protein recovered (SIgA/TP, IgG/TP), bronchial washings recovered from the uninvolved lung of lung cancer patients demonstrated a significantly decreased SIgA/TP ratio compared to control subjects (.14 ± .02 vs .31 ± .05, SEM, p
Databáze: OpenAIRE