Pregnancy after CMV infection following uterus transplantation: A case report from the Dallas Uterus Transplant Study
| Autor: | Matthew Rosenzweig, W Cedric, Liza Johannesson, Anji Wall, Giuliano Testa |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Infertility
Transplantation medicine.medical_specialty Pregnancy Obstetrics Opportunistic infection business.industry Uterus Congenital cytomegalovirus infection virus diseases 030230 surgery medicine.disease Embryo transfer 03 medical and health sciences 0302 clinical medicine Infectious Diseases medicine.anatomical_structure Uterus transplantation medicine 030211 gastroenterology & hepatology business Complication |
| Zdroj: | Transplant Infectious Disease. 23 |
| ISSN: | 1399-3062 1398-2273 |
| DOI: | 10.1111/tid.13653 |
| Popis: | Uterus transplantation is a repeatedly proven treatment for women with absolute uterine-factor infertility, which is the congenital or acquired absence of the uterus, who desire to carry, and ultimately deliver, a child. No stranger to the field of transplant or obstetrics is cytomegalovirus. Cytomegalovirus is both a frequent complication after transplant, presenting as an opportunistic infection, as well as a common congenital disease in the newborn child from pregnancy. To date, there have been no reported cases of pregnancy following uterus transplantation from cytomegalovirus-positive donors into cytomegalovirus-negative recipients. We present a case report describing our experience of a cytomegalovirus-negative recipient, transplanted with a uterus from a cytomegalovirus-positive living donor, and subsequently diagnosed with active cytomegalovirus infection despite prophylactic treatment. She was treated for infection prior to embryo transfer and carried a healthy child to term. This case suggests transplanting a cytomegalovirus-positive uterus into a negative donor is possible to do safely. |
| Databáze: | OpenAIRE |
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