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Nanotechnology is a multidisciplinary science in the fields of Physics, Chemistry and Biology. Nanoparticles have a large surface area to volume ratio and high surface energy. Due to this characteristic feature; it opens up new scope for its various applications. In this study, we have reported the synthesis of silver nanoparticles (AgNP) from silver nitrate (AgNO3) using the underutilized fruit of Elaeagnus pyriformis fruit juice in an optimized reaction. During synthesis, solution color changes from yellow to brownish due to reduction of Ag⁺ into Ag⁰ (AgNP) by phytocompounds (fatty acid and its derivatives) of E. pyriformis fruit juice. To know the presence and involvement of bioactive compounds as a reducing and capping agent the AgNPs were extensively characterized by UV-Vis spectroscopy, SEM (Scanning electron microscopy), FESEM (Field emission scanning electron microscopy), EDX (Energy-dispersive X-ray), XRD (X-ray diffraction analysis)and FTIR (Fourier transformed infrared spectroscopy). Furthermore, the antioxidant efficacy of AgNP was determined and significant antimicrobial activity was recorded against human pathogenic micro organisms. To know the efficacy as a potent anticancerous agent, in-silico molecular docking analysis was done using anti-apoptotic protein Bcl-XL and preliminary results indicate that AgNPs may have the potency to combat cancer by manipulating apoptosis. |
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