Captopril-induced lichen planus pemphigoides
| Autor: | Houssem Hmouda, Najet Ghariani, Lilia Chenguel, Kamel Bouraoui, Mohamed Denguezli, Chaker Ben Salem |
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| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
integumentary system Epidemiology business.industry Captopril medicine.disease Dermatology Lichen planus pemphigoides body regions stomatognathic diseases Corticosteroid therapy Lichenoid eruption Rare case medicine Oral steroid therapy Pharmacology (medical) Bullous pemphigoid skin and connective tissue diseases business Adverse drug reaction medicine.drug |
| Zdroj: | Pharmacoepidemiology and Drug Safety. 17:722-724 |
| ISSN: | 1053-8569 |
| DOI: | 10.1002/pds.1618 |
| Popis: | Purpose To report a rare case of lichen planus pemphigoides (LPP) possibly induced by captopril. Case summary A 74-year-old woman developed pruriginous and bullous lichenoid eruption after starting captopril for hypertension. Histopathological and immunological features were consistent with the diagnosis of LPP that was managed by discontinuing captopril and corticosteroid therapy. Eight months after the cessation of oral steroid therapy, no relapse had occurred. Discussion LPP, a rare skin disorder, has been generally considered to represent a mixture of clinical, histopathological and immunological patterns of lichen planus and bullous pemphigoid. It is predominantly idiopathic. However, in rare cases it has been associated with the administration of drugs. Here we present a typical LPP related to the use of captopril. Conclusions Clinicians should be aware of the ability of captopril to induce LPP. Copyright © 2008 John Wiley & Sons, Ltd. |
| Databáze: | OpenAIRE |
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