An ultrastructural study of infantile fibrosarcoma of the mandible

Autor: Masafumi Mimura, Shizuko Ichinose, Yutaka Kimijima, Kuo Jeng Hsieh, Nobuyuki Tanaka, Takao Miyamoto, Kodo Sasaki, Teruo Amagasa
Rok vydání: 1995
Předmět:
Zdroj: Medical Electron Microscopy. 28:76-79
ISSN: 1860-1499
0918-4287
DOI: 10.1007/bf02348023
Popis: A rare case of infantile fibrosarcoma in a mandible was investigated by light and electron microscopic observation. The usual features of malignancy may not accurately predict malignant behavior in infantile fibrosarcoma. We investigated the correlation between the clinical- and the morphological features of the tumor. All tumor tissues were highly cellular, and the tumor cells were often arranged in a herring bone-like pattern. Most of them were spindle-shaped. Electron microscopic observation revealed the rough endoplasmic reticulum, whose constituent cisternae were dilated and contained amorphous or granular material, resembling macrophages. These ultrastructural findings might be related to the good clinical course of the presented case.
Databáze: OpenAIRE