| Autor: |
Attya Zaheer, Ashiq Hussain, Shazia Tufail, Faiza Irshad, Fatima Qaiser, Shakeela Nazir, Mufassar Nishat |
| Rok vydání: |
2022 |
| Zdroj: |
Pakistan Journal of Medical and Health Sciences. 16:438-440 |
| Popis: |
Fluvastatin's hepatoprotective impact is being investigated in the current study. It is possible that the oxidative stress pathway is implicated in PCM hepatotoxicity. The acute hepatotoxicity of PCM was investigated in this study. Place of study: Rashid Latif Medical College Lahore Materials and Methods: The rabbits were divided into five groups of ten each. The saline group received (the vehicle). Fluvastatin (20 mg/kg), PCM (600 mg/kg), and PCM + 10 mg Fluvastatin (600 mg PCM + 20 mg Fluvastatin) were administered to the animals. The livers from all the animals were taken out and cleansed. 70% alcohol was used for washing extensively, after which the liver tissue was embedded in paraffin and then 5 mm thick paraffin slices were stained by aid of hematoxylin and eosin. Results: Male rabbits were shown to be harmful to paracetamol (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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