Usefulness of repeated presentation of Mini-Mental State Examination as a diagnostic procedure - a population-based study
Autor: | H. Heinonen, Eeva-Liisa Helkala, Aulikki Nissinen, Jaakko Tuomilehto, H. Soininen, Kari Alhainen, Merja Hallikainen, Miia Kivipelto |
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Rok vydání: | 2002 |
Předmět: |
Pediatrics
medicine.medical_specialty Psychometrics Population Neurological disorder 03 medical and health sciences 0302 clinical medicine mental disorders medicine Dementia Medical history 030212 general & internal medicine education education.field_of_study Mini–Mental State Examination medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine medicine.disease Surgery Neurology Neurology (clinical) business Chest radiograph 030217 neurology & neurosurgery |
Zdroj: | Acta Neurologica Scandinavica. 106:341-346 |
ISSN: | 0001-6314 |
DOI: | 10.1034/j.1600-0404.2002.01315.x |
Popis: | Helkala E-L, Kivipelto M, Hallikainen M, Alhainen K, Heinonen H, Tuomilehto J, Soininen H, Nissinen A. Usefulness of repeated presentation of Mini-Mental State Examination as a diagnostic procedure – a population-based study. Acta Neurol Scand 2002: 106: 341–346. © Blackwell Munksgaard 2002. Material and methods– The 280 subjects who achieved 24 points or less in the Mini-Mental State Examination (MMSE) in the first survey of 1449 subjects were invited for a comprehensive diagnostic examination for dementia including medical history, thorough neurological and cardiovascular examinations and detailed neuropsychological evaluation, magnetic resonance imaging (MRI)-study, cerebrospinal fluid (CSF)-analysis, electrocardiogram (ECG), chest radiograph and blood tests after the first assessment. The MMSE was presented again. Results– Out of 240 persons, 57 subjects were diagnosed as having dementia. When the cut-off point of 24 or less in the second MMSE was used, the sensitivity of the second MMSE was 82% and the specificity was 64%. The positive predictive value of the second MMSE was 42% and negative predictive value 92%. The non-demented subjects improved their MMSE score at the second examination. In contrast, the demented subjects maintained their low MMSE score at the second examination. |
Databáze: | OpenAIRE |
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