| Autor: | Anton L. Bryantsev, Yu. G. Antropova, Eduard Tararak, Natalia Kalinina, O. P. Il'inskaya |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Cell division
General Medicine Cell cycle Biology Molecular biology General Biochemistry Genetics and Molecular Biology In vitro Cell biology chemistry.chemical_compound Cell nucleus medicine.anatomical_structure chemistry Cyclin-dependent kinase medicine biology.protein Cell aging Bromodeoxyuridine Cyclin |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 134:81-83 |
| ISSN: | 0007-4888 |
| DOI: | 10.1023/a:1020677209755 |
| Popis: | Experiments with bromodeoxyuridine showed that the count of nonproliferating cells in a monolayer culture of aortic endothelial cells from adult humans rapidly increased during long-term subculturing. Cytochemical assay showed that these cells contain neutral b-galactosidase, the marker of aging cells. Immunocytochemical assay demonstrated that most cells express p53 protein and inhibitor of the cell cycle p21WAF1. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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