A Randomised, Single-blind, Crossover Comparison of the Acceptability of the Calcium and Vitamin D3 Supplements Calcichew D3 Forte® and Ad Cal D3® in Elderly Patients
| Autor: | Trevor P. Rees, Ian Howe |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Vitamin
medicine.medical_specialty business.industry chemistry.chemical_element General Medicine Calcium Crossover study Surgery law.invention Clinical trial chemistry.chemical_compound Swallowing chemistry Randomized controlled trial law Internal medicine medicine Vitamin D and neurology Single blind business |
| Zdroj: | Current Medical Research and Opinion. 16:245-251 |
| ISSN: | 1473-4877 0300-7995 |
| Popis: | SummaryBackground: Supplements of calcium and vitamin D are given to elderly patients in order to reduce the likelihood of osteoporotic fractures. The acceptability of the preparation is an important component of the compliance of such patients with their treatment.Aim: To compare the acceptability of Calcichew D3 Forte (CDF) and Ad Cal D3 (ACD).Method: This was a randomised, crossover, comparative study of two formulations of calcium and vitamin D. Patients took CDF for seven days followed by ACD for seven days, or vice versa, according to the randomisation schedule. At the end of each treatment period, patients used visual analogue scales (VAS) to indicate the grittiness, chalkiness, taste, ease of chewing, ease of swallowing and stickiness of each preparation.Results: One hundred and two elderly patients taking calcium supplements were recruited. Of these, 94 were suitable for inclusion in the efficacy analysis. The VAS scores were significantly lower for CDF than for ACD for grittiness (p = 0.0051), c... |
| Databáze: | OpenAIRE |
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