The Effect of n-Butanol Extraction of Potentilla anserina L. on Hypoxia-Induced Inflammatory Factors Expression of Wistar Rat Cortical Neuron
| Autor: | Yong Liang Zhang, Ling Zhi Li, Jing Sun, Bin Meng, Wen Li Xie, Hong Sheng Gao, Guang Ming Song, Ling Wang, Zhen Yang |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Cell physiology Programmed cell death Physiology General Medicine Pharmacology Hypoxia (medical) Biology Neuroprotection 03 medical and health sciences Electrophysiology 030104 developmental biology 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis medicine Tumor necrosis factor alpha Neuron medicine.symptom Homeostasis |
| Zdroj: | MOJ Anatomy & Physiology. 3 |
| ISSN: | 2471-139X |
| DOI: | 10.15406/mojap.2017.03.00102 |
| Popis: | The study aims to investigate the effects of n butanol extraction of Potentilla anserina L NP on cortical neuronal cultures and subject to h of oxygen deprivation hypoxia like injury The investigation demonstrated that NP at and mg ml effectively prevented the decrease of neuron survival rates and the increase of LDH release after exposure of cortical cultures to h oxygen deprivation These results indicated that NP has neuroprotective effect against neuronal cell death induced by oxygen deprivation High throughout suspension array technology for simultaneous detection of multiple inflammatory factors expression showed that IL beta IL and TNF alpha participated in the neuroprotective effect against oxygen deprivation induced neuronal death nbsp |
| Databáze: | OpenAIRE |
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