Updates on the multimodality management of desmoplastic small round cell tumor

Autor: Dillip Mudaly, Rajni Yadav, Ashwin A Kallianpur, Suryanarayan V.S. Deo, Ramanathan M. Palaniappan, Praveen Yadav, Nootan Kumar Shukla
Rok vydání: 2012
Předmět:
Zdroj: Journal of Surgical Oncology. 105:617-621
ISSN: 0022-4790
DOI: 10.1002/jso.22130
Popis: Desmoplastic Small Round Cell Tumor (DSRCT) is a rare and an aggressive malignancy with poor outcome. This tumor can co-express epithelial, neural, and mesenchymal markers. The molecular hallmark of DSRCT is the EWS–WT1 fusion protein. Despite the diversities in treatment modality, the best results have been seen with radical surgery and adjuvant or neoadjuvant chemotherapy. J. Surg. Oncol. 2012; 105:617–621. © 2011 Wiley Periodicals, Inc.
Databáze: OpenAIRE