Multifocal Electroretinograms in Stargardt's Disease/Fundus Flavimaculatus
| Autor: | Kazuki Kuniyoshi, Mikki Arai, Tatsuo Hirose, Hiroko Terasaki |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
genetic structures medicine.diagnostic_test biology business.industry ABCA4 Retinal General Medicine Macular degeneration Fundus (eye) Macular dystrophy medicine.disease Fluorescein angiography eye diseases Sensory Systems Stargardt disease Ophthalmology chemistry.chemical_compound chemistry medicine biology.protein sense organs business Electroretinography |
| Zdroj: | Ophthalmologica. 232:118-125 |
| ISSN: | 1423-0267 0030-3755 |
| DOI: | 10.1159/000361056 |
| Popis: | Purpose: To determine whether the characteristics of multifocal electroretinograms (mfERGs) were correlated with the ophthalmic appearance of the fundus in patients with Stargardt's disease/fundus flavimaculatus (SFF). Methods: Full-field ERGs, mfERGs, and general ophthalmic examinations were performed on 49 eyes with SFF. Results: The SFF patients were divided into four subtypes according to the classification of Noble and Carr [Arch Ophthalmol 1979;97:1281-1285]. The patients with type 1 SFF had severely reduced mfERGs in the macular area and reduced and delayed responses in the mid-periphery. The type 2 SFF patients had reduced but recordable mfERGs from the center of the macula with more depressed responses in the paramacular area, and the type 3 SFF patients had reduced and delayed mfERGs both in the macula and periphery. The patients with type 4 SFF had normal mfERGs in the macular area and delayed responses in all outer zones. Conclusions: These mfERG findings indicate that each subtype of SFF has unique characteristics corresponding to the abnormal retinal functions. |
| Databáze: | OpenAIRE |
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