Helicobacter pylori and Healing of Refractory Duodenal Ulcer: Preliminary Results of a Randomised Trial
| Autor: | M. Lazzaroni, G. Bianchi Porro, O. Sangaletti, H. Zhu |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
medicine.medical_specialty
biology medicine.drug_class business.industry Incidence (epidemiology) Antibiotics Rapid urease test Helicobacter pylori biology.organism_classification Asymptomatic Gastroenterology digestive system diseases Duodenal ulcer Sucralfate Refractory Internal medicine medicine medicine.symptom business medicine.drug |
| Zdroj: | Helicobacter pylori and Gastroduodenal Pathology ISBN: 9783642774881 |
| Popis: | Helicobacter pylori (HP) infection is very frequently observed in patients suffering from gastric and, in particular, duodenal ulcer with a mean incidence of 60% and 86%, respectively, as opposed to a 24% occurrence in asymptomatic volunteers [1]. HP infection of the gastric antrum is considered potentially capable of influencing ulcer healing rates and may well play a role in duodenal ulcer resistance to H2 antagonists. To explore the possibility of HP involvement, we undertook a randomised study of refractory duodenal ulcers comparing the efficacy of colloidal bismuth subcitrate (CBS) plus antibiotics active on HP with that of sucralfate, a drug with similar anti-ulcer properties but devoid of anti-HP activity. |
| Databáze: | OpenAIRE |
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