Impact of Carotid Endarterectomy upon Cognitive Functioning
| Autor: | Francesca Crawley, Martin M. Brown, Sarah Lunn, Michael J. G. Harrison, Stanton Newman |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Cognition Carotid endarterectomy Disease medicine.disease Surgery Cognitive test Neurology Sample size determination medicine Neurology (clinical) Cognitive skill Cardiology and Cardiovascular Medicine business Stroke Endarterectomy Clinical psychology |
| Zdroj: | Cerebrovascular Diseases. 9:74-81 |
| ISSN: | 1421-9786 1015-9770 |
| DOI: | 10.1159/000015901 |
| Popis: | Background and Purpose: The extent to which carotid endarterectomy (CEA) influences cognitive functioning has been the subject of a number of studies often with conflicting conclusions. This paper systematically reviews the literature in an attempt to clarify this issue. Results: Although the majority of studies (16/28) reported an improvement in cognition after surgery, a substantial minority (12/28) found no change. Studies before 1984 tended to report an improvement, while later studies tended to report no change in cognition. Cognitive improvement was also more likely the longer the time interval between CEA and assessment. The studies were found to differ on many methodological factors, e.g. sample size, type of patient and control group, severity and side of carotid stenosis, the range of cognitive tests and timing of postoperative assessment. Conclusion: Given the conflicting findings, and the methodological issues, it is not possible to draw a clear conclusion regarding the impact of carotid endarterectomy upon cognition. Future research which pays attention to these methodological factors is needed in order to adequately resolve the current debate. |
| Databáze: | OpenAIRE |
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