A Simulation Study of Cell Separation in Microfluidic Channel Based on Hydrodynamic Principle
| Autor: | Muhammad Asraf Mansor, Ida Laila Ahmad, Mohd Ridzuan Ahmad |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Materials science
010401 analytical chemistry Microfluidics Ranging 02 engineering and technology 021001 nanoscience & nanotechnology 01 natural sciences Finite element method 0104 chemical sciences Microfluidic channel Cell separation Fluid dynamics Hydrodynamic technique Microparticle 0210 nano-technology Biological system |
| Zdroj: | 2018 IEEE-EMBS Conference on Biomedical Engineering and Sciences (IECBES). |
| DOI: | 10.1109/iecbes.2018.8626646 |
| Popis: | Separation micro-particles based on physical characteristics is important in numerous applications such as diagnostics, biological analyses, food industries and chemical processing. Microfluidic devices have emerged as a multifunctional and powerful platform for separation ranging from nano-micro sized particles to biological cells. This paper presents a simulation study for microparticle separation in a microfluidic channel based on hydrodynamic technique. By exploiting the hydrodynamic properties of the fluid flow and physical characteristics of microparticles, effective size-based separation is demonstrated. The objectives of the simulations are to obtain the appropriate channels’ angle to separate micro-particle. The analysis of effects of taper angle for microparticle separation was carried out using numerical solutions from the finite element ABAQUS-FEA software. The taper angles 20° and 25° are successfully separate the mixture of 1000 kgm−3 and 10000 kgm−3 density microparticle. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|