| Autor: |
John Gillard, Claire Ashman, Horacio Salomon, Elizabeth Hooker, Haolun Jin, Antonietta R. Belmonte, Nick Cammack, Colleen A. Evans, Wei Wang, Mark A. Wainberg, Bernard Belleau, Dilip M. Dixit, Tarek S. Mansour, H. L. Allan Tse |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Nucleosides, Nucleotides and Nucleic Acids. 14:627-635 |
| ISSN: |
1525-7770 |
| Popis: |
3′-Oxa-4′-thiocytidine nucleoside analogues 14–17 were prepared from oxathiolanes 10 and 11, and evaluated for activity against HIV-1 and HBV in vitro. The nucleoside analogues were found to possess potent activities against HIV-1 in a panel of cell lines. Compound 16 is moderately active against HBV in 2.2.15 cells. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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