Development of a monoclonal-based enzyme-linked immunosorbent assay for the coccidiostat salinomycin

Autor:	Ross C. Beier, Marcel H. Elissalde, Loyd D. Rowe, Larry H. Stanker
Rok vydání:	1993
Předmět:	chemistry.chemical_classification Coccidiostat medicine.drug_class Narasin General Chemistry Limiting Biology Monoclonal antibody Molecular biology Microbiology chemistry.chemical_compound Enzyme chemistry Coccidiostats Monoclonal medicine General Agricultural and Biological Sciences Salinomycin
Zdroj:	Journal of Agricultural and Food Chemistry. 41:2167-2171
ISSN:	1520-5118 0021-8561
DOI:	10.1021/jf00035a066
Popis:	The polyether ionophoric coccidiostats are an important class of antimicrobials because of their extensive global use in modern agriculture. Salinomycin, the most widely used ionophoric anticoccidial in the U.S. broiler industry, has been marketed in all of the poultry-producing countries of the world. Established methods of analysis of salinomycin have disadvantages limiting their utility. We report here the development of 16 monoclonal anti-salinomycin antibodies. These monoclonal antibodies were used in competition enzyme-linked immunosorbent asays to differentially recognize salinomycin and the structurally similar narasin in the 10 ppb range
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b2a5384e7e143fcf59c34becfe1d1116 https://doi.org/10.1021/jf00035a066 Zobrazit plný text záznamu