Ultrastructure of human amniotic membrane covering villous chorion and smooth chorion in preeclampsia

Autor: O Evirgen, O Semiz, S Akkuş, A Heper Okçu, R Aytaç, H Ilkay
Rok vydání: 2008
Předmět:
Zdroj: EMC 2008 14th European Microscopy Congress 1–5 September 2008, Aachen, Germany ISBN: 9783540852278
Popis: Amniotic membrane consists of amniotic epithelium, avascular compact layer and fibroblastic layer. The fusion of amniotic membrane with chorion occurs in 12th week of pregnancy. Amniotic fluid and uterin wall deep layers nourishes amnion epithelium. Basal face infoldings extend to basal lamina which is rich in proteoglicans and heparan sulphate that acts as a permeability barrier for macromolecules. Preeclampsia is a maternal disorder characterised by hypertension and proteinuria after 20th week of gestation.Decreased placental perfusion causes hypoxia and release of cytotoxic factors. [1, 2] The aim of this study was to evaluate the possible structural changes of amniochorionic membrane taken from the area of placental disc (central) and from the free reflected membranes (peripheric) of preeclamptic placentas by light and electron microscopy.
Databáze: OpenAIRE