A facile synthesis of functionally complex isoxazole derivatives

Autor:	Chorng Shyr Niou, Nicholas R. Natale
Rok vydání:	1984
Předmět:	Metalation Chemistry Stereochemistry Organic Chemistry Oxazoline Alkylation Ring (chemistry) Biochemistry Acid catalysis chemistry.chemical_compound Drug Discovery Electrophile Isoxazole Selectivity
Zdroj:	Tetrahedron Letters. 25:3943-3946
ISSN:	0040-4039
DOI:	10.1016/0040-4039(84)80036-2
Popis:	Metalation of 2(4′-Isoxazolyl)-Δ 2 -oxazolines takes place initially and selectively on the C-5′-alkyl group. Subsequent metalation also proceeds at this position. Selective deprotection of the oxazoline was accomplished without disturbing the isoxazole ring.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b29aff9642dc43075780b4a2383a4da5 https://doi.org/10.1016/0040-4039(84)80036-2 Zobrazit plný text záznamu