Stellenwert der Lipoproteinelektrophorese für die quantitative Bewertung von Plasmalipoproteinen

Autor: H.-J. Lisch, Herbert Braunsteiner, Ch. Breier, Heinz Drexel
Rok vydání: 2008
Předmět:
Zdroj: DMW - Deutsche Medizinische Wochenschrift. 111:1888-1890
ISSN: 1439-4413
0012-0472
DOI: 10.1055/s-2008-1068730
Popis: The reliability of semiquantitative densitometric lipoprotein electrophoresis was compared with that of the quantitative determination of plasma lipoproteins by zonal ultracentrifugation on plasma from 73 patients. As an alternative to the measurement of lipoproteins by electrophoresis other, simple laboratory methods were used and also compared with plasma lipoprotein concentrations obtained by zonal ultracentrifugation. It was found that quantitative measurement of plasma lipoproteins by densitometric electrophoresis correlated positively to actual plasma concentration by zonal ultracentrifugation, but other simple methods of lipid determination--of plasma cholesterol; of triglycerides; of HDL and LDL cholesterol--are definitely better for obtaining plasma lipoprotein concentrations. Lipoprotein electrophoresis should not be used for the quantitative determination of plasma lipoproteins.
Databáze: OpenAIRE