Effect of Low-Frequency Stimulation on Spontaneous Firing in Cultured Neuronal Networks

Autor:	P.S. Wolters, A. van Ooyen, J. van Pelt, G.J.A. Ramakers, Ildiko Vajda
Rok vydání:	2008
Předmět:	Cortical tissue nervous system Chemistry Spike train Period (gene) Biological neural network Stimulation sense organs Multielectrode array skin and connective tissue diseases Neuroscience Cultured neuronal network Low frequency stimulation
Zdroj:	Advances in Cognitive Neurodynamics ICCN 2007 ISBN: 9781402083860
DOI:	10.1007/978-1-4020-8387-7_11
Popis:	Cultured neuronal networks from dissociated rat cortical tissue show spontaneous firing activity from about the end of the first week in vitro. Multielectrode recordings have shown slow developmental changes in the firing activity at the individual electrode sites. Here we report that a short period of low-frequency electrical stimulation is able to induce lasting changes in the spontaneous firing activity, significantly larger than developmental changes over similar periods of time.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b295260613b85a1086490a8694b52ee8 https://doi.org/10.1007/978-1-4020-8387-7_11 Zobrazit plný text záznamu