The synthesis of amide derivatives of the sodium salt of p-aminosalicylic acid by reaction with carboxyl containing copolymer chains

Autor:	O. F. Ginzburg, V. M. Bondarenko, V. G. Rupyshev, A. F. Nikolaev
Rok vydání:	1975
Předmět:	Pharmacology chemistry.chemical_classification P-Aminosalicylic Acid Chemistry Pharmacology toxicology Polymer Condensation reaction Sodium salt chemistry.chemical_compound Amide Drug Discovery Polymer chemistry Copolymer Organic chemistry Peptide bond
Zdroj:	Pharmaceutical Chemistry Journal. 9:616-618
ISSN:	1573-9031 0091-150X
DOI:	10.1007/bf00758685
Popis:	We have investigated the condensation reaction of a series of synthetic carboxyl containing (co)polymers (I) with an antitubercular preparation, viz., the sodium salt of paminosalicylic acid (II) under the action of N,N'-dicyclohexylcarbodiimide (III), with the aim of making potentially physiologically active preparations in which p-aminosalicylic acid (PAS~ is ll~nked with the polymer by an amide bond.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b2939187f76384f926fe3b65d6ddce7d https://doi.org/10.1007/bf00758685 Zobrazit plný text záznamu Full text from SpringerLink