Synthesis and study of basic hydrolysis of novel derivatives of N-[(adamantan-1-yl)methyl]aniline
Autor: | A. S. Babushkin, A. A. Vernigora, Boris S. Orlinson, M. B. Navrotskii, Ivan A. Novakov, S. N. Voloboev, I. A. Kirillov |
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Rok vydání: | 2016 |
Předmět: | |
Zdroj: | Russian Journal of General Chemistry. 86:2599-2605 |
ISSN: | 1608-3350 1070-3632 |
DOI: | 10.1134/s1070363216120057 |
Popis: | Using the Leuckart–Wallach reaction, novel conformationally flexible structural analogs of Bromantane drug have been synthesized from 3-haloadamantane-1-carbaldehydes. Basic hydrolysis of the prepared compounds has been studied as a model of one of the pathways of their transformations in vivo. |
Databáze: | OpenAIRE |
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