Synthesis and study of basic hydrolysis of novel derivatives of N-[(adamantan-1-yl)methyl]aniline

Autor: A. S. Babushkin, A. A. Vernigora, Boris S. Orlinson, M. B. Navrotskii, Ivan A. Novakov, S. N. Voloboev, I. A. Kirillov
Rok vydání: 2016
Předmět:
Zdroj: Russian Journal of General Chemistry. 86:2599-2605
ISSN: 1608-3350
1070-3632
DOI: 10.1134/s1070363216120057
Popis: Using the Leuckart–Wallach reaction, novel conformationally flexible structural analogs of Bromantane drug have been synthesized from 3-haloadamantane-1-carbaldehydes. Basic hydrolysis of the prepared compounds has been studied as a model of one of the pathways of their transformations in vivo.
Databáze: OpenAIRE