Chemical Composition and Anti-Leishmania Major Activity of Essential Oils from Artemesia spp. Grown in Central Tunisia
| Autor: | Mouna Sdiri, Safia El-Bok, Mohamed Fethi Diouani, Ahmed Mathlouthi, Mossadok Ben-Attia, Abdelaziz Souli, Mouna Belkessam |
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| Rok vydání: | 2018 |
| Předmět: |
biology
Traditional medicine Artemisia herba-alba Chamazulene 030231 tropical medicine Organic Chemistry Artemisia campestris biology.organism_classification 01 natural sciences Biochemistry Absinthium 0104 chemical sciences Analytical Chemistry law.invention 010404 medicinal & biomolecular chemistry 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry law Artemisia Artemisia absinthium Medicinal plants Essential oil |
| Zdroj: | Journal of Essential Oil Bearing Plants. 21:1186-1198 |
| ISSN: | 0976-5026 0972-060X |
| DOI: | 10.1080/0972060x.2018.1526128 |
| Popis: | Natural products are a very important source of bio-molecules for drug to treat infectious diseases. New antileishmanial agents are timely needed, due to leishmania toxicity, drug-resistant strains and high costs treatments. In this study, we report the chemical characterization and antileishmanial activity of oil extracts from three medicinal plants belonging to genus Artemisia (Asteracea), that grow in central Tunisia. The chemical composition of volatile compounds had been elucidated by gas chromatography-mass spectroscopy analysis. Chemical analysis revealed that essential oils were composed of 34 compounds: α-thujone (29.3%), chamazulene (39.2%) and β-pinene (32%), were the main constituents for the essential oils of Artemesia herba alba, Artemesia absinthium and Artemesia campestris, respectively. The hydrodistilled essential oils from these three species of Artemisia showed significant anti-leishmanial activities against Leishmania major. Oils from A. herba alba, A. absinthium and A. campes... |
| Databáze: | OpenAIRE |
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