Assembling Synthons in a Chiral Form: Equivalence of 6H, 12H-Dibenzo[b,f][1,5]dithiocin-S,S′-dioxide to Two Chiral Benzyl Units

Autor:	Elisa Piga, Sergio Cossu, Giulia Licini, Ottorino De Lucchi
Rok vydání:	1992
Předmět:	chemistry.chemical_compound chemistry Stereochemistry Organic Chemistry Drug Discovery Synthon Enantioselective synthesis Diastereomer chemistry.chemical_element Sulfoxide Chirality (chemistry) Biochemistry Sulfur
Zdroj:	Tetrahedron Letters. 33:2053-2054
ISSN:	0040-4039
DOI:	10.1016/0040-4039(92)88139-v
Popis:	Two benzyl groups can be assembled with a chiral shape in the 6 H , 12 H -Dibenzo[ b,f ][1,5]dithiocine structure which can be resolved into its antipods via enantioselective oxidation to the bissulfoxide. The latter affords one single diastereoisomer in the methylation of its bis-anion. The two sulfur atoms serve as linking agents, holder and transmitter of chirality, and activating functionalities.
Databáze:	OpenAIRE
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