| Autor: |
Yongqiang Li, Xiaodong Zhang, Chijian Li, Shisi Li, Shiyi Liang, YiHao Guo, Ge Qian, Yuxiang Huang, Weicheng Xv |
| Rok vydání: |
2020 |
| Popis: |
Background- Blood Oxygen Level-Dependent Magnetic Resonance Imaging (BOLD-MRI) provide regional measurements of oxygen content using deoxyhemoglobin paramagnetic characteristics. Metabolic Syndrome (MS) could affect renal oxygenation, which have an impact on the clinical course of the disease. The goal of this study was to evaluate BOLD-MRI findings in kidneys of male patients with MS.Materials and Methods- A total of 24 males patients with MS were collected in the hospital and 24 male volunteers were selected as the control group. All volunteers underwent a renal scan using 3.0T magnet (Philips, Achieva). R2* of the renal cortex and medulla was measured on BOLD images.Results- Medullary R2* (MR2*) and Medulla/Cortex R2* ratio（MCR） were significantly lower in MS patients (MR2*=24.39±2.18 s−1, MCR=1.29±0.14) than in controls (MR2*=28.21±4.70s−1, MCR=1.53±0.28 ) (P2* (CR2*) values were not significantly different between the two group. Conclusions- The MR2* and MCR were lower in male patients with MS compared to controls. MR2*and MCR were potential imaging biomarkers for prediction of early renal impairment in male MS. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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