Letter by Singh Regarding Article, 'Enalapril in Infants With Single Ventricle: Results of a Multicenter Randomized Trial'
| Autor: | Tajinder P. Singh |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Pediatrics
medicine.medical_specialty Study groups business.industry medicine.disease Placebo law.invention medicine.anatomical_structure Randomized controlled trial Ventricle law Physiology (medical) Heart failure medicine Population study Enalapril Cardiology and Cardiovascular Medicine business Specific population medicine.drug |
| Zdroj: | Circulation. 123 |
| ISSN: | 1524-4539 0009-7322 |
| Popis: | To the Editor: The study, “Enalapril in Infants with Single Ventricle: Results of a Multicenter Randomized Trial” enrolled 230 infants with a single ventricle before their cavopulmonary connection surgery, randomized them to enalapril or placebo, and found no difference in somatic growth among study groups during the next 9 months.1 The major rationale for the study was equipoise among pediatric cardiologists with respect to benefit from angiotensin-converting enzyme inhibitors in the study population. Although the study demonstrates adequately what it set out to do, the findings are applicable to the specific population only and cannot be generalized to all children with heart failure, not … |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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