Studies on culture age versus exometabolite production in batch cultures of the cyanobacterium Nostoc insulare

Autor:	Rainer-B. Volk
Rok vydání:	2007
Předmět:	Indole test Cell growth media_common.quotation_subject Plant physiology Plant Science Aquatic Science Biology Antimicrobial Competition (biology) chemistry.chemical_compound Biosynthesis chemistry Biochemistry Cyanobacterium nostoc Secondary metabolism media_common
Zdroj:	Journal of Applied Phycology. 19:491-495
ISSN:	1573-5176 0921-8971
DOI:	10.1007/s10811-007-9161-z
Popis:	Changes in the content of exometabolites excreted by the cyanobacterium Nostoc insulare during batch cultivation were determined. During linear growth, only the non-toxic compound N,N′-(4,5-dimethyl-1,2-phenylene)-bis-acetamide was detectable in appreciable quantities in the medium, whereas during stationary growth the antimicrobial and cytotoxic exometabolites 4,4′-dihydroxybiphenyl and 9H-pyrido(3,4-b)indole (norharmane) were also present to an increasing degree. Hence it is proposed that biosynthesis of N,N′-(4,5-dimethyl-1,2-phenylene)bis-acetamide in N. insulare is associated with cell proliferation and primary metabolism of this organism. 4,4′-Dihydroxybiphenyl and norharmane, however, are proposed to be products of secondary metabolism that are excreted by N. insulare primarily under nutrient-restricted conditions and under increased pressure of competition with other organisms.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b25d9dad4ea1f16b12d54d6b9ef04031 https://doi.org/10.1007/s10811-007-9161-z Zobrazit plný text záznamu Full text from SpringerLink