Stereoselective syntheses of siphonarienal and siphonarienone

Autor:	Supriya Ghanty, Chinta Krinda Suresh Kumar, B. V. Subba Reddy
Rok vydání:	2015
Předmět:	Stereochemistry Organic Chemistry Grignard reaction Total synthesis Alkylation Catalysis Stereocenter Kinetic resolution Inorganic Chemistry chemistry.chemical_compound Siphonarienal chemistry Wittig reaction Stereoselectivity Physical and Theoretical Chemistry
Zdroj:	Tetrahedron: Asymmetry. 26:885-890
ISSN:	0957-4166
Popis:	The asymmetric total synthesis of marine polypropionate natural products siphonarienal and siphonarienone has been achieved from a common precursor 3 . The key transformations of this synthesis are the diastereoselective oxidative kinetic resolution, Wittig olefination, Grignard reaction, and Evans asymmetric alkylation for the installation of a third stereogenic center of the target molecules from commercially available starting materials.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b251950d6cb42d5da2b370b46fa86701 https://doi.org/10.1016/j.tetasy.2015.07.001 Zobrazit plný text záznamu Full Text from ScienceDirect