IN FRAME DELETION OF INTRON-7 IN THE P53 GENE IN A HUMAN TONSIL TUMOR

Autor:	Ilona Lewensohn-Fuchs, Zsofia Berke, Kp Magnusson, George Klein, T Dallianis, K G Wiman, Eva Munck-Wikland
Rok vydání:	1995
Předmět:	Genetics Cancer Research Oncogene Intron Cell cycle Biology Molecular medicine medicine.anatomical_structure stomatognathic system Oncology Tonsil medicine Coding region Allele Gene
Zdroj:	International Journal of Oncology.
ISSN:	1791-2423 1019-6439
DOI:	10.3892/ijo.6.1.27
Popis:	We here report a unique intron deletion in the p53 gene. Analysis of a human tonsil tumor that expressed elevated levels of p53 showed a deletion of the entire intron 7 in one of the p53 alleles, leaving the coding sequence intact. The significance of the intron 7 deletion for the development of the tonsil tumor is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b23ea2f13437d9370e23053b44742114 https://doi.org/10.3892/ijo.6.1.27 Zobrazit plný text záznamu