Variability and identification power of 60 X-chromosome in two native Siberian populations
| Autor: | V. N. Kharkov, Vadim Stepanov, A. V. Bocharova, A. A. Cherednichenko, L. I. Minaicheva, K. V. Vagaitseva |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Genetics endocrine system Genetic diversity 030102 biochemistry & molecular biology Single-nucleotide polymorphism Biology Dna identification Genetic differentiation Random matching 03 medical and health sciences 030104 developmental biology Multilocus genotype Allele frequency X chromosome |
| Zdroj: | Russian Journal of Genetics. 52:433-435 |
| ISSN: | 1608-3369 1022-7954 |
| DOI: | 10.1134/s1022795416030157 |
| Popis: | Genetic diversity of 60 X-chromosome single nucleotide polymorphisms (XSNPid panel) in populations of Siberian Tatars and Tuvinians is described. A close spectrum of allele frequencies and a low level of their genetic differentiation (Gst = 0.021) is revealed. High discriminating power of the XSNPid panel in populations under study is demonstrated. The random matching probability (MP) of multilocus genotypes in males is 1.12 × 10–18 in Siberian Tatars and 7.77 × 10–16 in Tuvans. In females, MP is several orders of magnitude lower: 1.51 × 10–25 in Siberian Tatars and 1.83 × 10–23 in Tuvinians. |
| Databáze: | OpenAIRE |
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