Daytime continuous polysomnography predicts MSLT results in hypersomnias of central origin
| Autor: | Raffaele Ferri, Giuseppe Plazzi, Stefania Detto, Francesca Poli, Fabio Pizza, Keivan Kaveh Moghadam, Emmanuel Mignot, Stefano Vandi |
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| Rok vydání: | 2012 |
| Předmět: |
Multiple Sleep Latency Test
Daytime Receiver operating characteristic medicine.diagnostic_test Cataplexy business.industry Cognitive Neuroscience Area under the curve Excessive daytime sleepiness General Medicine Polysomnography medicine.disease Behavioral Neuroscience Anesthesia mental disorders medicine medicine.symptom business Narcolepsy |
| Zdroj: | Journal of Sleep Research. 22:32-40 |
| ISSN: | 0962-1105 |
| DOI: | 10.1111/j.1365-2869.2012.01032.x |
| Popis: | SUMMARY In the diagnostic work-up of hypersomnias of central origin, the complaint of excessive daytime sleepiness should be objectively confirmed by MSLT findings. Indeed, the features and diagnostic utility of spontaneous daytime sleep at 24 h continuous polysomnography (PSG) have never been investigated. We compared daytime PSG features to MSLT data in 98 consecutive patients presenting with excessive daytime sleepiness and with a final diagnosis of narcolepsy with cataplexy ⁄hypocretin deficiency (n = 39), narcolepsy without cataplexy (n = 7), idiopathic hypersomnia without long sleep time (n = 19), and hypersomnia with normal sleep latency at MSLT (n = 33). Daytime sleep time was significantly higher in narcolepsy-cataplexy but similar in the other groups. Receiver operating characteristics (ROC) curves showed that the number of naps during daytime PSG predicted a mean sleep latency £8 min at MSLT with an area under the curve of 0.67 ± 0.05 (P = 0.005). The number of daytime sleep-onset REM periods (SOREMPs) in spontaneous naps strikingly predicted the scheduled occurrence of two or more SOREMPs at MSLT, with an area under the ROC curve of 0.93 ± 0.03 (P |
| Databáze: | OpenAIRE |
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