Efecto de los componentes del síndrome metabólico en la función pulmonar. El inesperado papel del colesterol ligado a lipoproteínas de alta densidad
| Autor: | Alberto Francisco Rubio-Guerra, Germán Vargas-Ayala, Saúl Huerta-Ramírez, Angélica Paniagua-Pérez, Andrés Ledesma-Velázquez, David Castro-Serna |
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| Rok vydání: | 2019 |
| Předmět: |
Spirometry
medicine.medical_specialty Vital capacity medicine.diagnostic_test business.industry Cholesterol 030230 surgery medicine.disease Pulmonary function testing 03 medical and health sciences FEV1/FVC ratio chemistry.chemical_compound 0302 clinical medicine High-density lipoprotein chemistry Internal medicine Diabetes mellitus medicine Cardiology Surgery Metabolic syndrome business |
| Zdroj: | Cirugía y Cirujanos. 86 |
| ISSN: | 0009-7411 |
| DOI: | 10.24875/ciru.m18000030 |
| Popis: | Background Metabolic syndrome is a condition that predisposes to cardiovascular disease and diabetes mellitus. In addition, it can have effects over neoplastic pathologies, liver and pulmonary function. Our objective is to analyze the effect of the metabolic syndrome and its components on pulmonary function. Method 110 subjects from Mexico City were evaluated and anthropometric measurements, glucose determination, triglycerides and high-density lipoprotein (HDL) cholesterol were made. They underwent a simple spirometry. Diagnosis of metabolic syndrome was made following the NCEP-ATPIII criteria. Results Of 110 individuals, 90 (82%) were women and 20 men (18%); 71 subjects (65%) presented metabolic syndrome. Subjects with central obesity had a forced vital capacity (FVC) lower than subjects without central obesity (2.72 vs. 3.11 liters; p < 0.05). Those with low HDL had better spirometric results than subjects with normal HDL (FEV1 2.36 vs. 1.85 liters; p < 0.05), FVC (2.95 vs. 2.45 liters; p < 0.05) and FEV1/FVC ratio (0.78 vs.74; p < 0.05). Hypertensive subjects presented lower volumes in FEV1 (1.91 vs. 2.38; p < 0.05) and FVC (2.49 vs. 2.99; p < 0.05). Conclusion There is no difference between the spirometry volumes of patients with metabolic syndrome versus the metabolically healthy subjects. The only factors associated with a decrease in FEV1 and FVC are central obesity and arterial hypertension. An unexpected finding was the negative correlation between HDL levels and lung function. |
| Databáze: | OpenAIRE |
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