The effect of magnetic field on the shape of etch pits of paracetamol crystals

Autor: V. I. Krasheninin, T. P. Shakhtshneider, Yu. A. Zakharov, V.V. Boldyrev, V. E. Ivashchenko, A. E. Ermakov
Rok vydání: 2002
Předmět:
Zdroj: Materials Research Innovations. 5:214-218
ISSN: 1433-075X
1432-8917
Popis: In the present study we investigate the effect of magnetic field on the shape of etch pits of the crystals of p-hydroxyacetanilide (paracetamol), which is widely used in pharmacy as antipyretic, antiphlogistic medicine. It was discovered that the magnetic field (H=0.5 T, τ=15 min) changes the morphology of etch pits and shifts dislocations in paracetamol crystal. Activation energy of the changes induced by the action of the magnetic field was determined to be 63 kJ/mol, which is comparable with the energy of hydrogen bonds in crystal lattice.
Databáze: OpenAIRE