Cell-Intrinsic CD38 Expression Sustains Exhausted CD8 + T Cells by Regulating Their Survival and Metabolism during Chronic Viral Infection

Autor: Julia M. DeRogatis, Emily N. Neubert, Karla M. Viramontes, Monique L. Henriquez, Dequina A. Nicholas, Roberto Tinoco
Rok vydání: 2023
Předmět:
Zdroj: Journal of Virology. 97
ISSN: 1098-5514
0022-538X
Popis: Our study shows how CD38 expression is regulated on CD8 + T cells responding during acute and chronic viral infection. We observed higher CD38 levels on CD8 + T cells during chronic viral infection compared to levels during acute viral infection.
Databáze: OpenAIRE