| Autor: |
Yee Liang Thian, Albert SC Low, Pierce KH Chow, London L Ooi, Alexander YF Chung, Shoen CS Low, Wanying Xie, Choon Hua Thng |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
Annals of the Academy of Medicine, Singapore. 40:454-459 |
| ISSN: |
0304-4602 |
| DOI: |
10.47102/annals-acadmedsg.v40n10p454 |
| Popis: |
Introduction: The 2005 American Association for Study of Liver Diseases (AASLD) diagnostic criteria allow non-invasive diagnosis of hepatocellular carcinoma (HCC) based on their enhancement pattern but we have observed a high incidence of atypical enhancement characteristics in HCC associated with portal vein thrombosis. This study seeks to examine the radiological features of this particular subgroup. Materials and Methods: Patients with HCC and portal vein thrombosis who underwent pre-treatment multiphasic CT imaging were drawn from a surgical database. The arterial, portal venous and delayed phase images were assessed qualitatively and quantitatively (with region of interest [ROI] analysis) for lesion hypervascularity and washout. The background enhancement of the left and right lobes of the liver was also quantified by ROI analysis. Results: Twenty-five lesions in 25 patients were selected for analysis. Qualitative analysis showed that 10/25 (40%) lesions demonstrated arterial hypervascularity while 16/25 (64%) lesions showed washout. Ten out of 25 (40%) lesions demonstrated both arterial hypervascularity and washout. Quantitative analysis showed that the average absolute lesion enhancement from precontrast to arterial phases was 49.1 (±17.1) HU for hypervascular lesions compared to 23.8 (±16.6) HU for non-hypervascular lesions (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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