| Autor: |
G Dembour, Catherine Barrea, M. Stijns, B Stos, Caroline Ovaert, Thierry Sluysmans, A Arape |
| Rok vydání: |
2004 |
| Předmět: |
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| Zdroj: |
Archives de Pédiatrie. 11:1197-1201 |
| ISSN: |
0929-693X |
| DOI: |
10.1016/j.arcped.2004.05.016 |
| Popis: |
Down's syndrome is the most frequent chromosomic anomaly. Fifty percent are associated with a congenital heart disease. Life expectancy and quality of life are increasing since 15 years with improving surgical techniques. PATIENTS AND METHODS: This study presents 73 patients with Down's syndrome who underwent a surgical repair of congenital heart disease between 1992 and 2002. Among them, 37 (50.6%) had a complete atrio-ventricular septal defect (AVSD) and 36 an other anomaly. RESULTS: Five children died in the post operative period: all had an AVSD. Two late deaths occurred due to extra cardiac causes during the follow up. Two children who underwent a repair of AVSD had to be reoperated. The majority of the children are doing well, without any cardiac symptom. Thirty-eight percent of patients with AVSD repair have a middle mitral or tricuspid regurgitation and three had a massive mitral or tricuspid regurgitation. One child presents neurological sequelae related to surgery. CONCLUSION: Congenital heart diseases in Down's syndrome can be repaired with a limited risk of death. Final results are good for many children with significant improvement of the quality of life and life expectancy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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Full Text from ScienceDirect