Thermal field and tissue damage analysis of cryoballoon ablation for atrial fibrillation
| Autor: | Binkai Xu, Baolin Liu, Ping Ye, Yuantong Xia |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Materials science
Therapeutic Technique 020209 energy medicine.medical_treatment Energy Engineering and Power Technology Atrial fibrillation 02 engineering and technology Lesion formation 030204 cardiovascular system & hematology Ablation medicine.disease Pennes equation Industrial and Manufacturing Engineering Pulmonary vein 03 medical and health sciences 0302 clinical medicine Tissue damage 0202 electrical engineering electronic engineering information engineering medicine Cryoballoon ablation Biomedical engineering |
| Zdroj: | Applied Thermal Engineering. 142:524-529 |
| ISSN: | 1359-4311 |
| DOI: | 10.1016/j.applthermaleng.2018.07.027 |
| Popis: | Cryoballoon ablation has emerged as a significant therapeutic technique to isolate pulmonary veins for the treatment of atrial fibrillation (AF). The temporal and spatial variation of the thermal field in clinical ablation is uncharted and cannot be measured in real time. Finite element analysis is used to study the temperature filed in the process of tissue cooling and lesion formation within the myocardium. In this paper, we established the 2D axisymmetric simplified model of pulmonary vein antrum and the temperature distribution was obtained by solving the Pennes equation coupled with the phase change model. Furthermore, the tissue damage integral analysis was adopted in our research which gives an indicator of tissue injury during the ablation. In order to verify the reliability of the model, in-vitro experiments were conducted using a porcine heart and clinical research conclusions were also quoted as a reference. |
| Databáze: | OpenAIRE |
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