The sequential embryo transfer compared to blastocyst embryo transfer in in vitro fertilization (IVF) cycle in patients with the three repeated consecutive IVF. A randomized controlled trial

Autor:	Fatemeh Bakhtiyari Ghaleh, Batool Hossein Rashidi, Fedyeh Haghollahi, Mamak Shariat, Elham Azimi-Nekoo, Elham Raisi, Ensieh Shahrokh Tehraninejad, Vahid Kalantari
Rok vydání:	2019
Předmět:	medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment 030209 endocrinology & metabolism law.invention 03 medical and health sciences 0302 clinical medicine Endocrinology Primary outcome Randomized controlled trial law medicine In patient Blastocyst reproductive and urinary physiology Gynecology 030219 obstetrics & reproductive medicine In vitro fertilisation business.industry Obstetrics and Gynecology Embryo Embryo transfer Pregnancy rate medicine.anatomical_structure embryonic structures business
Zdroj:	Gynecological Endocrinology. 35:955-959
ISSN:	1473-0766 0951-3590
DOI:	10.1080/09513590.2019.1613639
Popis:	The purpose of this study was to determine the pregnancy rate in the double sequential transfer of embryos on both day 3 and day 5 compared to day 5 alone, in in vitro fertilization-embryo transfer (IVF/ET) in patients with the three repeated consecutive IVF failures. In this controlled trial, women scheduled for IVF/ET with the three repeated consecutive IVF failures were randomized to either sequential transfer of embryos on day 2 and on day 5 after ovum pick-up (group 1, n = 60) or blastocyst ET on day 5 (group 2, n = 60) as a control group. The primary outcome measures were the chemical and clinical pregnancy rate. Baseline and cycle characteristics were comparable in both groups. Chemical and clinical pregnancy rate was similar in the sequential ET group (40%) compared to the day 5 of ET group (38.3%) (p value = .85). It seems that the double ET does not increase the chance of pregnancy rate compared to blastocyst ET on day 5 in the patients with the three repeated IVF-ET failures.
Databáze:	OpenAIRE
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