Development of Aseptic Renal Abscess in a Patient with Non-Small-Cell Lung Cancer with ALK Translocation during Crizotinib Treatment

Autor:	Publio Cesar Cavalcante Viana, Manuel Santos da Cruz Neto, Artur Katz, Luciana Franco do Prado de Carvalho, Lucila Soares da Silva Rocha, Esper George Kallas, Andrea K. Shimada
Rok vydání:	2015
Předmět:	Oncology medicine.medical_specialty Pathology Crizotinib Side effect medicine.drug_class business.industry General Medicine medicine.disease Tyrosine-kinase inhibitor Renal Abscess Internal medicine ROS1 medicine Cyst Aseptic processing Lung cancer business medicine.drug
Zdroj:	Advances in Lung Cancer. :53-57
ISSN:	2169-2726 2169-2718
DOI:	10.4236/alc.2015.44007
Popis:	Background: Crizotinib is a tyrosine kinase inhibitor of ALK, MET and ROS1. In a safety database trial, it was suggested an association of Crizotinib with the development of renal cyst in patients with non-small-cell lung cancer (NSCLC). Aim: To report an uncommon side effect of Crizotinib in a patient with NSLC. Case Presentation: We report the case of a 68-year-old woman with NSCLC who developed bilateral progressive aseptic renal abscesses during Crizotinib treatment. Conclusion: Further studies may be necessary to determinate the risk of renal cyst development and the management of these complications.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b1b4c054cf7238e7210347335ccdd3a8 https://doi.org/10.4236/alc.2015.44007 Zobrazit plný text záznamu