Cytotoxic activity of methanol extraction of Avicennia marina and taurin in the HeLa cancer cells

Autor:	Endang Widiastuti, N. Nurcahyani, E. rosa, H. Busman, S. Andriani
Rok vydání:	2021
Předmět:	History biology Chemistry Extraction (chemistry) biology.organism_classification Computer Science Applications Education HeLa chemistry.chemical_compound Biochemistry Avicennia marina Cancer cell Cytotoxic T cell Methanol
Zdroj:	Journal of Physics: Conference Series. 1751:012045
ISSN:	1742-6596 1742-6588
DOI:	10.1088/1742-6596/1751/1/012045
Popis:	The aim of study was to determine any anticancer potential from Avicennia marina leaf extract compare to taurine on cytotoxic and anti-proliferation activities against HeLa cervical cancer cell line by using the MTT method (3-(4, 5-dimethylthiazol-2-yl))-2, 5-diphenyltetrazolium bromide). The results indicated that methanol extraction of A. marina leaf as well as taurine did have cytotoxic and anti-proliferation effects on HeLa cell line with IC50 values of 321 ppm and 603 ppm 1000 ppm. While the doubling time value for anti-proliferation of A. marina leaf methanol extraction and taurine showed higher values than the control group (72.19 hours).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b1ab4fb2ca909c9230151fe427e1f5fe https://doi.org/10.1088/1742-6596/1751/1/012045 Zobrazit plný text záznamu